# Introduction

## Background

OncoKB™ is a Precision Oncology Knowledgebase that contains information about the biological effects and treatment implications of specific cancer genes and their somatic alterations. OncoKB™ is developed and maintained by the Knowledge Systems group in the Marie Josée and Henry R. Kravis Center for Molecular Oncology at the Memorial Sloan Kettering Cancer Center (MSK).

## OncoKB™ Processes

The schematic shows a summary of the data sources, knowledgebase architecture and processes that compose the OncoKB™ workflow. As is shown, OncoKB™ curators will keep monitoring data changes from multiple data sources and edit changed content via OncoKB™ curation platform. Next step, the Lead Scientists will review modified content to approve/reject it. Once it gets approval, it will be send to database and updated to OncoKB™ Access in realtime.

![Summary of OncoKB™ processes](https://623726595-files.gitbook.io/~/files/v0/b/gitbook-legacy-files/o/assets%2F-M2noZm_5yXK2lyMYR1S%2F-M33gkY4MWd0H4n7iRN5%2F-M33nTapdFebVai4K393%2Fprocess.png?alt=media\&token=e8bf1a7a-6a2e-4f67-a5d1-963433520fa6)


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# Agent Instructions: Querying This Documentation

If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.

Perform an HTTP GET request on the current page URL with the `ask` query parameter:

```
GET https://api.oncokb.org/master.md?ask=<question>
```

The question should be specific, self-contained, and written in natural language.
The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.