# Introduction

## Background

OncoKB™ is a Precision Oncology Knowledgebase that contains information about the biological effects and treatment implications of specific cancer genes and their somatic alterations. OncoKB™ is developed and maintained by the Knowledge Systems group in the Marie Josée and Henry R. Kravis Center for Molecular Oncology at the Memorial Sloan Kettering Cancer Center (MSK).

## OncoKB™ Processes

The schematic shows a summary of the data sources, knowledgebase architecture and processes that compose the OncoKB™ workflow. As is shown, OncoKB™ curators will keep monitoring data changes from multiple data sources and edit changed content via OncoKB™ curation platform. Next step, the Lead Scientists will review modified content to approve/reject it. Once it gets approval, it will be send to database and updated to OncoKB™ Access in realtime.

![Summary of OncoKB™ processes](https://623726595-files.gitbook.io/~/files/v0/b/gitbook-legacy-files/o/assets%2F-M2noZm_5yXK2lyMYR1S%2F-M33gkY4MWd0H4n7iRN5%2F-M33nTapdFebVai4K393%2Fprocess.png?alt=media\&token=e8bf1a7a-6a2e-4f67-a5d1-963433520fa6)